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HIV-1 drug resistance testing at second-line regimen failure in Arua, Uganda: avoiding unnecessary switch to an empiric third-line.

Abstract

OBJECTIVES: The number of patients on second-line antiretroviral therapy is growing, but data on HIV drug resistance patterns at failure in resource-constrained settings are scarce.

Fily F Ayikobua E Ssemwanga D Nicholas S Kaleebu P Delaugerre C Pasquier E Amoros Quiles I Balkan S Schramm B
Tropical medicine & international health : TM & IH 2018 Oct ; 23(10); 1075-1083. doi: 10.1111/tmi.13131. Epub 2018 10 02
HIV-1 Ouganda Uganda VIH-1 drug resistance résistance aux médicaments second-line antiretroviral therapy traitement antirétroviral de seconde ligne

Determinants of dietary practices during pregnancy: A longitudinal qualitative study in Niger.

Abstract

Undernutrition is associated with maternal morbidity and poor pregnancy outcomes. This qualitative study seeks to understand the multilevel factors influencing maternal dietary practices in Niger, including the impact of pregnancy illnesses on diet.

Rosen JG Clermont A Kodish SR Matar Seck A Salifou A Grais RF Isanaka S
Maternal & child nutrition 2018 10 ; 14(4); e12629. doi: 10.1111/mcn.12629. Epub 2018 06 28
Niger diet maternal nutrition nutrition during pregnancy pregnancy outcomes qualitative research

MUAC as the sole discharge criterion from community-based management of severe acute malnutrition in Burkina Faso.

Abstract

The use of mid upper arm circumference (MUAC) measurement to screen and determine eligibility for admission to therapeutic feeding programs has been established, but evidence and programmatic experience to inform guidance on the use of MUAC as a discha

Isanaka S Hanson KE Frison S Andersen CT Cohuet S Grais RF
Maternal & child nutrition 2018 Sep 08; e12688. doi: 10.1111/mcn.12688. Epub 2018 09 08
Burkina Faso community-based management of acute malnutrition discharge mid upper arm circumference proportional weight gain severe acute malnutrition

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.

Abstract

BACKGROUND: Treatment outcomes for multidrug-resistant tuberculosis remain poor.

Ahmad N Ahuja SD Akkerman OW Alffenaar JC Anderson LF Baghaei P Bang D Barry PM Bastos ML Behera D Benedetti A Bisson GP Boeree MJ Bonnet M Brode SK Brust JCM Cai Y Caumes E Cegielski JP Centis R Chan PC Chan ED Chang KC Charles M Cirule A Dalcolmo MP D'Ambrosio L de Vries G Dheda K Esmail A Flood J Fox GJ Fréchet-Jachym M Fregona G Gayoso R Gegia M Gler MT Gu S Guglielmetti L Holtz TH Hughes J Isaakidis P Jarlsberg L Kempker RR Keshavjee S Khan FA Kipiani M Koenig SP Koh WJ Kritski A Kuksa L Kvasnovsky CL Kwak N Lan Z Lange C Laniado-Laborín R Lee M Leimane V Leung CC Leung EC Li PZ Lowenthal P Maciel EL Marks SM Mase S Mbuagbaw L Migliori GB Milanov V Miller AC Mitnick CD Modongo C Mohr E Monedero I Nahid P Ndjeka N O'Donnell MR Padayatchi N Palmero D Pape JW Podewils LJ Reynolds I Riekstina V Robert J Rodriguez M Seaworth B Seung KJ Schnippel K Shim TS Singla R Smith SE Sotgiu G Sukhbaatar G Tabarsi P Tiberi S Trajman A Trieu L Udwadia ZF van der Werf TS Veziris N Viiklepp P Vilbrun SC Walsh K Westenhouse J Yew WW Yim JJ Zetola NM Zignol M Menzies D
Lancet (London, England) 2018 09 08; 392(10150); 821-834. doi: 10.1016/S0140-6736(18)31644-1. Epub 2018 10 22

Outbreak of Pneumococcal Meningitis, Paoua Subprefecture, Central African Republic, 2016-2017.

Abstract

We report a pneumococcal meningitis outbreak in the Central African Republic (251 suspected cases; 60 confirmed by latex agglutination test) in 2016-2017. Case-fatality rates (10% for confirmed case-patients) were low.

Coldiron ME Touré O Frank T Bouygues N Grais RF
Emerging infectious diseases 2018 09 ; 24(9); 1720-1722. doi: 10.3201/eid2409.171058. Epub 2019 01 18
Central African Republic Streptococcus pneumoniae bacteria meningitis meningitis/encephalitis outbreak pneumococcal meningitis pneumococcal vaccines

Micro-Hotspots of Risk in Urban Cholera Epidemics.

Abstract

Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting.

Azman AS Luquero FJ Salje H Mbaïbardoum NN Adalbert N Ali M Bertuzzo E Finger F Toure B Massing LA Ramazani R Saga B Allan M Olson D Leglise J Porten K Lessler J
The Journal of infectious diseases 2018 Aug 24; 218(7); 1164-1168. doi: 10.1093/infdis/jiy283. Epub 2018 11 14

Voluntary Community Human Immunodeficiency Virus Testing, Linkage, and Retention in Care Interventions in Kenya: Modeling the Clinical Impact and Cost-effectiveness.

Abstract

Background: In southwest Kenya, the prevalence of human immunodeficiency virus (HIV) infection is about 25%.

Luong Nguyen LB Yazdanpanah Y Maman D Wanjala S Vandenbulcke A Price J Parker RA Hennequin W Mendiharat P Freedberg KA
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Aug 16; 67(5); 719-726. doi: 10.1093/cid/ciy173. Epub 2018 11 14

A dynamic model of transmission and elimination of peste des petits ruminants in Ethiopia.

Abstract

Peste des petits ruminants (PPR), a devastating viral disease of sheep and goats, has been targeted by the global community for eradication within the next 15 years.

Fournié G Waret-Szkuta A Camacho A Yigezu LM Pfeiffer DU Roger F
Proceedings of the National Academy of Sciences of the United States of America 2018 08 14; 115(33); 8454-8459. doi: 10.1073/pnas.1711646115. Epub 2018 07 27
control elimination eradication mathematical model vaccination