Publications

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Carriage prevalence and serotype distribution of Streptococcus pneumoniae prior to 10-valent pneumococcal vaccine introduction: A population-based cross-sectional study in South Western Uganda, 2014.

Abstract

BACKGROUND: Information on Streptococcus pneumoniae nasopharyngeal (NP) carriage before the pneumococcal conjugate vaccine (PCV) introduction is essential to monitor impact.

Nackers F Cohuet S le Polain de Waroux O Langendorf C Nyehangane D Ndazima D Nanjebe D Karani A Tumwesigye E Mwanga-Amumpaire J Scott JAG Grais RF
Vaccine 2017 09 18; 35(39); 5271-5277. doi: 10.1016/j.vaccine.2017.07.081. Epub 2017 08 04
Adult Children Nasopharyngeal carriage Pneumococcal conjugate vaccine Pneumococcal serotypes Streptococcus pneumoniae Uganda

Prevalence of antibodies to Brucella species in commercial raw bovine milk in Southwestern Uganda.

Abstract

OBJECTIVES: The purpose and objective of this research was to explore the prevalence of antibodies against Brucella species in raw milk samples collected in Southwestern Uganda, one of the biggest milk producing regions in the Country.

Kamwine M Orikiriza P Taseera K Iramiot JS Ojuka P Ikiriza S Atwebembeire J Otieno D Tweshengyereze S Mwanga-Amumpaire J Bazira J Boum Y
BMC research notes 2017 Sep 08; 10(1); 215. doi: 10.1186/s13104-017-2537-5. Epub 2017 09 08
Brucellosis Diagnosis Indirect ELISA Milk ring test

A guide to aid the selection of diagnostic tests.

Abstract

In recent years, a wide range of diagnostic tests has become available for use in resource-constrained settings. Accordingly, a huge number of guidelines, performance evaluations and implementation reports have been produced.

Kosack CS Page AL Klatser PR
Bulletin of the World Health Organization 2017 Sep 01; 95(9); 639-645. doi: 10.2471/BLT.16.187468. Epub 2017 06 26

Adherence, tolerability, and outcome after 36 months of isoniazid-preventive therapy in 2 rural clinics of Swaziland: A prospective observational feasibility study.

Abstract

Although efficacy of 36 months isoniazid preventive therapy (IPT) among HIV-positive individuals has been proven in trial settings, outcome, tolerance, and adherence have rarely been evaluated in real-life settings.This is a prospective observational c

Mueller Y Mpala Q Kerschberger B Rusch B Mchunu G Mazibuko S Bonnet M
Medicine 2017 Sep ; 96(35); e7740. doi: 10.1097/MD.0000000000007740. Epub 2017 09 11

Prospective cohort study of the feasibility and yield of household child tuberculosis contact screening in Uganda.

Abstract

SETTING: Screening and isoniazid preventive therapy (IPT) of child contacts of tuberculosis (TB) patients is poorly implemented in resource-limited countries, in part due to difficulties in TB diagnosis in children.

Bonnet M Kyakwera C Kyomugasho N Atwine D Mugabe F Nansumba M Ii YB Mwanga-Amumpaire J Kiwanuka J
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2017 08 01; 21(8); 862-868. doi: 10.5588/ijtld.16.0889. Epub 2018 04 26

Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling study.

Abstract

BACKGROUND: Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings.

Blaizot S Huerga H Riche B Ellman T Shroufi A Etard JF Ecochard R
BMC infectious diseases 2017 07 26; 17(1); 522. doi: 10.1186/s12879-017-2612-5. Epub 2017 07 26
Antiretroviral therapy HIV Male circumcision Mathematical models Pre-exposure prophylaxis South Africa
Isanaka S Djibo A Grais RF
The New England journal of medicine 2017 07 20; 377(3); 302. doi: 10.1056/NEJMc1705793. Epub 2017 07 24

HIV misdiagnosis in sub-Saharan Africa: performance of diagnostic algorithms at six testing sites.

Abstract

INTRODUCTION: We evaluated the diagnostic accuracy of HIV testing algorithms at six programmes in five sub-Saharan African countries.

Kosack CS Shanks L Beelaert G Benson T Savane A Ng'ang'a A Andre B Zahinda JB Fransen K Page AL
Journal of the International AIDS Society 2017 07 03; 20(1); 21419. doi: 10.7448/IAS.20.1.21419. Epub 2017 11 16
HIV RDT algorithm diagnostic misdiagnosis test

Trends in one-year cumulative incidence of death between 2005 and 2013 among patients initiating antiretroviral therapy in Uganda.

Abstract

Recent ecological data demonstrate improving outcomes for HIV-infected people in sub-Saharan Africa. Recently, Uganda has experienced a resurgence in HIV incidence and prevalence, but trends in HIV-related deaths have not been well described.

Bebell LM Siedner MJ Musinguzi N Boum Y Bwana BM Muyindike W Hunt PW Martin JN Bangsberg DR
International journal of STD & AIDS 2017 07 ; 28(8); 800-807. doi: 10.1177/0956462416671431. Epub 2016 09 20
Africa Death HIV antiretroviral antiretroviral therapy clinical outcomes early mortality