Publications

Cholera Rapid Test with Enrichment Step Has Diagnostic Performance Equivalent to Culture.

Abstract

Cholera rapid diagnostic tests (RDT) could play a central role in outbreak detection and surveillance in low-resource settings, but their modest performance has hindered their broad adoption.

Ontweka LN Deng LO Rauzier J Debes AK Tadesse F Parker LA Wamala JF Bior BK Lasuba M But AB Grandesso F Jamet C Cohuet S Ciglenecki I Serafini M Sack DA Quilici ML Azman AS Luquero FJ Page AL
PloS one 2016 ; 11(12); e0168257. doi: 10.1371/journal.pone.0168257. Epub 2016 12 19

Ebola Virus Disease Complications as Experienced by Survivors in Sierra Leone.

Abstract

BACKGROUND: Thousands of people have survived Ebola virus disease (EVD) during the ongoing outbreak. However, data about the frequency and risk factors of long-term post-EVD complications remain scarce.

Tiffany A Vetter P Mattia J Dayer JA Bartsch M Kasztura M Sterk E Tijerino AM Kaiser L Ciglenecki I
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 06 01; 62(11); 1360-1366. doi: 10.1093/cid/ciw158. Epub 2016 03 21
Ebola complications survivors

Encouraging impact following 2.5 years of reinforced malaria control interventions in a hyperendemic region of the Republic of Guinea.

Abstract

BACKGROUND: Malaria is one of the principal causes of morbidity and mortality in the Republic of Guinea, particularly in the highly endemic regions.

Tiffany A Moundekeno FP Traoré A Haile M Sterk E Guilavogui T Genton B Serafini M Grais RF
Malaria journal 2016 05 28; 15(1); 298. doi: 10.1186/s12936-016-1353-z. Epub 2016 05 28
Cross sectional surveys Guinea Hyperendemic Malaria Plasmodium falciparum Prevalence Symptomatic

Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data.

Abstract

BACKGROUND: Gametocytes are responsible for transmission of malaria from human to mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte carriage, dependent upon host, parasite and pharmacodynamic factors.

BMC medicine 2016 May 24; 14 79. doi: 10.1186/s12916-016-0621-7. Epub 2016 05 24
Drug resistance Gametocyte Malaria Plasmodium falciparum

Potential impact of multiple interventions on HIV incidence in a hyperendemic region in Western Kenya: a modelling study.

Abstract

BACKGROUND: Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings.

Blaizot S Maman D Riche B Mukui I Kirubi B Ecochard R Etard JF
BMC infectious diseases 2016 Apr 29; 16 189. doi: 10.1186/s12879-016-1520-4. Epub 2016 04 29
Antiretroviral therapy HIV Hyperendemic settings Male circumcision Mathematical models Pre-exposure prophylaxis

Implementation and Operational Research: Feasibility of Using Tuberculin Skin Test Screening for Initiation of 36-Month Isoniazid Preventive Therapy in HIV-Infected Patients in Resource-Constrained Settings.

Abstract

INTRODUCTION: The tuberculin skin test (TST) can be used to identify HIV-infected people who would benefit the most from long-term isoniazid preventive therapy (IPT).

Huerga H Mueller Y Ferlazzo G Mpala Q Bevilacqua P Vasquez B Noël Mekiedje C Ouattara A Mchunu G Weyenga HO Varaine F Bonnet M
Journal of acquired immune deficiency syndromes (1999) 2016 Apr 01; 71(4); e89-95. doi: 10.1097/QAI.0000000000000895. Epub 2016 07 06

The "Buruli Score": Development of a Multivariable Prediction Model for Diagnosis of Mycobacterium ulcerans Infection in Individuals with Ulcerative Skin Lesions, Akonolinga, Cameroon.

Abstract

BACKGROUND: Access to laboratory diagnosis can be a challenge for individuals suspected of Buruli Ulcer (BU). Our objective was to develop a clinical score to assist clinicians working in resource-limited settings for BU diagnosis.

Mueller YK Bastard M Nkemenang P Comte E Ehounou G Eyangoh S Rusch B Tabah EN Trellu LT Etard JF
PLoS neglected tropical diseases 2016 Apr ; 10(4); e0004593. doi: 10.1371/journal.pntd.0004593. Epub 2016 04 05

A graphical method to assess distribution assumption in group-based trajectory models.

Abstract

Group-based trajectory models had a rapid development in the analysis of longitudinal data in clinical research. In these models, the assumption of homoscedasticity of the residuals is frequently made but this assumption is not always met.

Elsensohn MH Klich A Ecochard R Bastard M Genolini C Etard JF Gustin MP
Statistical methods in medical research 2016 04 ; 25(2); 968-82. doi: 10.1177/0962280213475643. Epub 2013 02 19
Checking assumptions grouped-based trajectory models homoscedasticity longitudinal data model adequacy

Global phylogeography and evolutionary history of Shigella dysenteriae type 1.

Abstract

Together with plague, smallpox and typhus, epidemics of dysentery have been a major scourge of human populations for centuries(1).

Njamkepo E Fawal N Tran-Dien A Hawkey J Strockbine N Jenkins C Talukder KA Bercion R Kuleshov K Kolínská R Russell JE Kaftyreva L Accou-Demartin M Karas A Vandenberg O Mather AE Mason CJ Page AJ Ramamurthy T Bizet C Gamian A Carle I Sow AG Bouchier C Wester AL Lejay-Collin M Fonkoua MC Le Hello S Blaser MJ Jernberg C Ruckly C Mérens A Page AL Aslett M Roggentin P Fruth A Denamur E Venkatesan M Bercovier H Bodhidatta L Chiou CS Clermont D Colonna B Egorova S Pazhani GP Ezernitchi AV Guigon G Harris SR Izumiya H Korzeniowska-Kowal A Lutyńska A Gouali M Grimont F Langendorf C Marejková M Peterson LA Perez-Perez G Ngandjio A Podkolzin A Souche E Makarova M Shipulin GA Ye C Žemličková H Herpay M Grimont PA Parkhill J Sansonetti P Holt KE Brisse S Thomson NR Weill FX
Nature microbiology 2016 03 21; 1 16027. doi: 10.1038/nmicrobiol.2016.27. Epub 2016 03 21