Publications

Detection of Plasmodium Species by High-Resolution Melt Analysis of DNA from Blood Smears Acquired in Southwestern Uganda.

Abstract

Microscopic diagnosis of malaria using Giemsa-stained blood smears is the standard of care in resource-limited settings.

Kassaza K Operario DJ Nyehangane D Coffey KC Namugosa M Turkheimer L Ojuka P Orikiriza P Mwanga-Amumpaire J Byarugaba F Bazira J Guler JL Moore CC Boum Y
Journal of clinical microbiology 2018 01 ; 56(1); . doi: 10.1128/JCM.01060-17. Epub 2017 12 26
PCR diagnostics high-resolution melting malaria

What's coming for health science and policy in 2018? Global experts look ahead in their field.

Abstract

In PLOS Medicine's first editorial of 2018, editorial board members and other leading researchers share their hopes, pleas, concerns, and expectations for this year in health research and policy.

Swaminathan S Room RS Ivers LC Hillis G Grais RF Bhutta ZA Byass P
PLoS medicine 2018 01 ; 15(1); e1002498. doi: 10.1371/journal.pmed.1002498. Epub 2018 01 30

Dried Blood Spots for Measuring Vibrio cholerae-specific Immune Responses.

Abstract

BACKGROUND: Vibrio cholerae causes over 2 million cases of cholera and 90,000 deaths each year.

Iyer AS Azman AS Bouhenia M Deng LO Anderson CP Graves M Kováč P Xu P Ryan ET Harris JB Sack DA Luquero FJ Leung DT
PLoS neglected tropical diseases 2018 01 ; 12(1); e0006196. doi: 10.1371/journal.pntd.0006196. Epub 2018 01 29

Four years of case-based surveillance of meningitis following the introduction of MenAfriVac in Moissala, Chad: lessons learned.

Abstract

OBJECTIVE: Case-based surveillance of bacterial meningitis in sentinel districts has been recommended after the introduction of the conjugated vaccine against Neisseria meningitidis serogroup A (NmA), MenAfriVac, in the African meningi

Page AL Coldiron ME Gamougam K Acyl MA Tamadji M Lastrucci C Hurtado N Tehoua FC Fermon F Caugant DA Porten K
Tropical medicine & international health : TM & IH 2017 12 ; 22(12); 1561-1568. doi: 10.1111/tmi.12987. Epub 2017 10 26
Chad Tchad bacterial meningitis latex agglutination tests meningococcal meningitis méningite bactérienne méningite pneumococcique méningite à méningocoques pneumococcal meningitis surveillance test d'agglutination au latex

Seasonal malaria chemoprevention: successes and missed opportunities.

Abstract

Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season.

Coldiron ME Von Seidlein L Grais RF
Malaria journal 2017 11 28; 16(1); 481. doi: 10.1186/s12936-017-2132-1. Epub 2017 11 28
Antimalarials Chemoprevention Malaria

Higher risk sexual behaviour is associated with unawareness of HIV-positivity and lack of viral suppression - implications for Treatment as Prevention.

Abstract

Efficacy of Treatment as Prevention Strategy depends on a variety of factors including individuals' likelihood to test and initiate treatment, viral load and sexual behaviour.

Huerga H Venables E Ben-Farhat J van Cutsem G Ellman T Kenyon C
Scientific reports 2017 Nov 23; 7(1); 16117. doi: 10.1038/s41598-017-16382-6. Epub 2017 11 23

Genomic history of the seventh pandemic of cholera in Africa.

Abstract

The seventh cholera pandemic has heavily affected Africa, although the origin and continental spread of the disease remain undefined.

Weill FX Domman D Njamkepo E Tarr C Rauzier J Fawal N Keddy KH Salje H Moore S Mukhopadhyay AK Bercion R Luquero FJ Ngandjio A Dosso M Monakhova E Garin B Bouchier C Pazzani C Mutreja A Grunow R Sidikou F Bonte L Breurec S Damian M Njanpop-Lafourcade BM Sapriel G Page AL Hamze M Henkens M Chowdhury G Mengel M Koeck JL Fournier JM Dougan G Grimont PAD Parkhill J Holt KE Piarroux R Ramamurthy T Quilici ML Thomson NR
Science (New York, N.Y.) 2017 11 10; 358(6364); 785-789. doi: 10.1126/science.aad5901. Epub 2018 04 10

Evaluation of the Deki Reader™, an automated RDT reader and data management device, in a household survey setting in low malaria endemic southwestern Uganda.

Abstract

BACKGROUND: Early diagnosis of suspected malaria cases with a rapid diagnostic test (RDT) has been shown to be an effective malaria control tool used in many resource-constrained settings.

Oyet C Roh ME Kiwanuka GN Orikiriza P Wade M Parikh S Mwanga-Amumpaire J Boum Y
Malaria journal 2017 11 07; 16(1); 449. doi: 10.1186/s12936-017-2094-3. Epub 2017 11 07
Deki Reader™ Malaria Malaria surveillance Rapid diagnostic test Uganda